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Updated: Aug 20, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Giant cell interstitial pneumonia: high-resolution CT and pathologic findings in four adult patients
Jin Wook Choi1, Kyung Soo Lee, Man Pyo Chung
1Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Ilwon-Dong, Kangnam-Ku, Seoul 135-710, Korea.
Objective:
The purpose of our study was to describe the high-resolution CT and pathologic findings of giant cell interstitial pneumonia (GIP) in four adult patients.
Conclusion:
GIP appears on high-resolution CT as ground-glass and irregular linear opacities in both lungs. These CT findings correspond histopathologically to areas of interstitial thickening caused by fibrosis and inflammatory cell infiltration and to areas of intraalveolar accumulation of macrophages and multinucleated giant cells.
