Related Experiment Video
Updated: Aug 20, 2026
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
Published on: December 28, 2017
Chemoradiotherapy for brain tumors: current status and perspectives
1Department of Neurosurgery, Saitama Medical School, 38 Morohongo, Moroyamamachi, Iruma-gun, Saitama, 350-0495, Japan. matutani@saitama-med.ac.jp
Abstract:
Brain tumors growing in the parenchyma of the brain infiltrate diffusely, and the role of surgery is restricted to maximal tumor-bulk removal. Residual tumor cells beyond the surgical margin are not killed by conventional radiation therapy with 60 'Gy. Many clinical trials delivering chemotherapy during radiation therapy and after radiation therapy have been performed, but the results remain poor. Here the author reviews the current treatments of gliomas, malignant lymphomas, medulloblastomas, and germ cell tumors, and their results.
Related Concept Videos
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:57Targeted Cancer Therapies
There are several types of targeted therapies against specific...