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Microstructured arrays with pre-synthesized capture probes for DNA detection based on metal nanoparticles and silver

Guo-Jun Zhang1, Robert Möller, Robert Kretschmer

  • 1Institute for Physical High Technology, PO Box 100239, 07702 Jena, Germany.

Journal of Fluorescence
|December 25, 2004
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...