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Updated: Aug 20, 2026
Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System
Published on: June 11, 2020
[Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats]
Jian-ming Tian1, Hao Li, Jin-mei Ye
1Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun 130021, Jilin, China.
Objective:
To investigate the protective effect of Ginsenoside Rg2 on Chemical myocardial ischemia.
Method:
The models of myocardial ischemia were built in rats with isoproterenol, sodium nitrite,pituitrin. Ginsenoside Rg2 (iv 2.5, 5.0, 10.0 mg x kg(-1)) were intravenously administered.
Result:
Ginsenoside Rg2 could improve the abnormal electrocardiogram (ECG), reduce the arca of myocardial ischemia and improve the abnormal zymologic value of myocardial.
Conclusion:
Ginsenoside Rg2 has inhibitory function on myocardialischemia.