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Updated: Aug 20, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
[Cephlometric analysis of the cranial base in class II(1) malocclusions with different vertical types in
1Shanghai Central Hospital of Yangpu District, Shanghai 200090, China.
Purpose:
To explore the morphology of the cranial base in Class II(1) malocclusions with different vertical types in adolescence.
Methods:
The sample of 60 males and 60 females were divided into Class II(1) high-angle group, average-angle group, and low-angle group and normal occlusion group. Each group had 30 cases. Cephalograms were analyzed for all subjects. Data were obtained to have analysis of variance and LSD multiple range test.
Results:
The cranial floor base angle (Ba-SE-FMS) of three groups with class II(1) malocclusion was increased. The anterior cranial floor angle was more open in the high angle group, and the flexure of the middle cranial floor was increased in the low angle and average angle groups. The 'effective vertical growth' of cranial floor was decreased while the mandibular plane angle was increased.
Conclusion:
The cranial floor base angle(Ba-SE-FMS) was suitable to describe the flexure of the cranial base, and indicated the mechanism of the Class II(1) malocclusion with different vertical types in adolescence.
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