A new chromone from Ficus lyrata

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Organic Chemistry

Background:

• Ficus lyrata, a plant species, is a potential source of bioactive natural products.
• Flavonoids and chromones are classes of compounds known for diverse biological activities.

Purpose of the Study:

• To isolate and characterize chemical constituents from the leaves of Ficus lyrata.
• To identify novel and known compounds for potential applications.

Main Methods:

• Phytochemical investigation involving isolation techniques.
• Structure elucidation using spectroscopic methods including IR, UV, 1H NMR, 13C NMR, and mass spectrometry.

Main Results:

• Isolation of a new chromone, 5,6-dihydroxy-2-methylchromone (FL-2).
• Identification of ten known compounds: beta-sitosterol-D-glucoside (FL-1), and eight flavonoids (FL-3 to FL-10).
• Structural confirmation of all isolated compounds through detailed spectral analysis.

Conclusions:

• The leaves of Ficus lyrata contain a diverse array of phytochemicals, including a novel chromone derivative.
• The established structures provide a basis for further investigation into the biological activities and potential uses of these compounds.