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Updated: Aug 20, 2026

An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
Two new alkaloids from the rhizome of Polygonatum sibiricum
Long-Ru Sun1, Xian Li, Su-Xian Wang
1School of Pharmacy, Shandong University, 44 West Wenhua Road, Jinan 250012, China. sunlr@sdu.edu.cn
Abstract:
Two new alkaloids named polygonatine A (1) and polygonatine B (2) have been isolated from the rhizome of Polygonatum sibiricum Redoute (Liliaceae). By spectral data (IR, UV, MS, 1D and 2D NMR) and chemical evidence, their structures were elucidated as 3-hydroxymethyl-5,6,7,8-tetrahydroindolizin-8-one (1) and 3-ethoxymethyl-5,6,7,8-tetrahydroindolizin-8-one (2).
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