Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anhydrobiosis.

J H Crowe1, F A Hoekstra, L M Crowe

  • 1Department of Zoology, University of California, Davis 95616.

Annual Review of Physiology
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Anhydrobiosis (anhydrobiosis) stabilization principles were identified, suggesting disaccharides like trehalose are key for cell survival during dehydration. These findings enable stabilization of various biological structures against drying.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of COVID-19 on the well-being of Victorian children born with cleft lip and/or palate.

Orthodontics & craniofacial research·2023
Same author

Characterization of large basking shark Cetorhinus maximus aggregations in the western North Atlantic Ocean.

Journal of fish biology·2018
Same author

Hydration State, Metabolism, and Hatching of Mono Lake Artemia Cysts.

The Biological bulletin·2018
Same author

Mitochondrial development and activity of binucleate and trinucleate pollen during germination in vitro.

Planta·2013
Same author

Protein synthesis of binucleate and trinucleate pollen and its relationship to tube emergence and growth.

Planta·2013
Same author

Social function assessment tools for children and adolescents: a systematic review from 1988 to 2010.

Clinical psychology review·2011

Area of Science:

  • Biochemistry
  • Cell Biology
  • Biophysics

Background:

  • Anhydrobiosis is a survival state in organisms exposed to dehydration.
  • Understanding the molecular mechanisms of anhydrobiosis is crucial for preserving biological materials.

Purpose of the Study:

  • To establish the fundamental principles governing the stabilization of living cells during anhydrobiosis.
  • To explore the potential of using specific molecules to confer desiccation tolerance to non-anhydrobiotic entities.

Main Methods:

  • Investigated the role of disaccharides, specifically trehalose and sucrose, in cellular stabilization.
  • Examined the stability of membrane vesicles, liposomes, and proteins under dehydration conditions.
  • Assessed the impact of lipid composition on survival during drying.

Related Experiment Videos

Main Results:

  • Identified key principles for stabilizing cells in anhydrobiosis.
  • Demonstrated that synthesis of disaccharides like trehalose is a primary factor for survival.
  • Showcased the potential to stabilize non-anhydrobiotic structures like liposomes and proteins.

Conclusions:

  • A single perturbation, such as trehalose synthesis, can be sufficient for anhydrobiotic survival.
  • While trehalose is crucial, additional adaptations are necessary for long-term stability, especially concerning lipid integrity.
  • The underlying physical principles of dry biological material stability are universal.