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Updated: Aug 20, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Sclerosing mesenteritis with occult ileal perforation: report of a case simulating extensive intra-abdominal
John Mathew1, Frank McKenna, John Mason
1Department of Surgery, Trafford General Hospital, Manchester, United Kingdom. mathewjohn9@aol.com
Abstract:
Sclerosing mesenteritis is a rare condition that is characterized by fibrosis affecting mainly small-bowel mesentery, which in extensive cases may mimic advanced intra-abdominal malignancy. Establishing the diagnosis in such cases is a clinical and histopathologic challenge. We report the successful management of a case of extensive sclerosing mesenteritis with occult ileal perforation, which was possibly the triggering cause. Severe complications occurred as a result of both the disease itself and its surgical treatment. Despite the complex course and life-threatening complications, a good prognosis can be expected. Although occasional recovery has been attributed to spontaneous regression and response to immunosuppressive therapy, a search for, and full eradication of, possible triggering focus is of paramount importance.
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