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Updated: Jul 16, 2026

An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers
Published on: December 1, 2017
[Past, present and future of anti-idiotype vaccination]
M Rodríguez Calvillo1, S Inogés, A López Díaz de Cerio
1Area de Terapia Celular de la Clínica Universitaria, Centro de Investigación Médica Aplicada, Facultad de Medicina, Universidad de Navarra, Pamplona. mrodriguec@unav.es
Abstract:
Cancer vaccines are conceived as therapeutic tools, in contrast to the prophylactic vaccines used to fight against infectious diseases. Among the most potent therapeutic vaccines, anti-idiotype vaccination is directed against the tumor idiotype, the only well-characterized tumor antigen displayed in neoplastic B-cells. Anti-idiotype vaccines have demonstrated clinical benefit against follicular lymphoma and are currently being evaluated in two different phase III clinical trials. Additional emerging strategies, which include the use of dendritic cells and the production of vaccines via molecular means will surely allow us to draw important conclusions concerning the treatment of cancer patients.
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