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Updated: Aug 20, 2026
Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad
Published on: January 20, 2019
[Pathological analysis of breast carcinoma after silicone gel injection]
Guo-qin Chen1, Rong Liu, Ying-ying Gu
1Department of Pathology, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China.
Objective:
To explore the correlation between breast carcinoma and silicone gel injection for breast augmentation.
Methods:
Four cases of breast cancer after silicone gel injection were studied by means of clinical pathological analysis.
Results:
In the four women, breast lump of over 5 cm in diameter was found half year to 2 years after silicone injection. The tumor was misdiagnosed to inflammatory reaction of silicone gel injection. Definite diagnosis was made by histological examinations, which showed there was mucoid, light blue and well-distributed silicone gel among the nests of neoplasm cells. Lymph node metastasis of cancer cells was observed.
Conclusions:
Silicone gel injection to the breast may be a reason for evoking or accelerating breast cancer. Breast cancer that occurred after breast augmentation with silicone gel injection could be misdiagnosed. Final diagnosis depends on biopsy. Silicone gel injection for breast augmentation should be abandoned.
