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Sesame seed allergy in children
P S E Agne1, E Bidat, P S E Agne
1Assistance publique-hôpitaux de Paris, Hôpital Ambroise Paré Boulogne, France.
European Annals of Allergy and Clinical Immunology
|December 30, 2004
Summary
Sesame seed allergy is increasingly common in children, presenting with various symptoms including edema and anaphylaxis. Some children may outgrow this allergy, but predictive criteria remain unclear.
Area of Science:
- Pediatric Allergy
- Food Hypersensitivity
- Immunology
Background:
- Sesame seed allergy is a growing concern in pediatric populations.
- Understanding its clinical manifestations and diagnostic approaches is crucial.
Purpose of the Study:
- To define the clinical signs of sesame seed allergy in children.
- To analyze allergological work-up results and demographic data.
- To investigate the outcome of sesame seed allergy.
Main Methods:
- Study involved 14 children diagnosed with sesame seed allergy across three French allergy centers.
- Diagnosis confirmed by clinical history, skin prick tests, and/or elevated specific IgE.
- Food challenge tests and reintroduction tests were utilized when necessary.
Main Results:
- The median age of onset was 5 years, with immediate reactions including edema, urticaria, and anaphylaxis.
- Positive skin prick tests showed a median wheal size of 5 mm; commercial extracts were less sensitive than native seeds.
- Elevated sesame specific IgE levels were observed (median 5.58 kUA/L).
- Three out of 14 children outgrew their allergy, indicated by decreasing IgE and negative skin tests.
Conclusions:
- Sesame seed allergy shares similarities with other food allergies.
- Spontaneous resolution of sesame seed allergy can occur, but predictive factors for this outcome are not yet defined.