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Allergic contact dermatitis to propolis.

Patricia T Ting1, Shane Silver

  • 1Faculty of Medicine, University of Calgary. pting@ucalgary.ca

Journal of Drugs in Dermatology : JDD
|December 31, 2004
PubMed
Summary
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Allergic contact dermatitis to propolis caused a 35-year-old woman's itchy foot blisters. Topical treatments failed, but diagnosis identified propolis allergy as the cause.

Area of Science:

  • Dermatology
  • Allergology
  • Contact Dermatitis

Background:

  • A 35-year-old woman presented with a two-week history of worsening, fluid-filled, itchy lesions on her right foot.
  • The patient had experienced minor trauma to the area and applied an over-the-counter propolis ointment.
  • She was also using prescribed medications including valacyclovir, ciprofloxacin, terbinafine cream, mupirocin ointment, and hydrocortisone cream without improvement.

Observation:

  • Physical examination revealed grouped erythematous papules that evolved into vesicles and bullae on the lateral aspect of the right foot.
  • Potassium hydroxide (KOH) scraping was negative, ruling out fungal infection.
  • The clinical presentation was consistent with allergic contact dermatitis.

Findings:

  • The patient was diagnosed with allergic contact dermatitis.

Related Experiment Videos

  • The suspected allergen was propolis, identified after topical application following minor foot trauma.
  • Failure of multiple prescribed topical treatments highlighted the need for accurate diagnosis.

    • Implications:

    • This case underscores the importance of considering allergic contact dermatitis to topical agents, even in the presence of seemingly unrelated prescribed treatments.
    • Accurate diagnosis is crucial for effective management, as demonstrated by the failure of empirical therapies.
    • Propolis, a natural substance, can act as a potent contact allergen, necessitating careful patient history taking regarding product use.