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Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
07:08

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

[Infant exposure to potentially toxic plasticizers in products for oral use]

Lilia Patricia Bustamante-Montes1, Beatriz Lizama-Soberanis, Flavio Vázquez-Moreno

  • 1Universidad Autónoma del Estado de Mexico, Toluca, Estado de México, México.

Salud Publica De Mexico
|December 31, 2004
PubMed

Insights

Oral product use in young children was 13%, with phthalate exposure below recommended limits. However, other sources may increase total exposure, necessitating further research into potential health effects.

Area of Science:

  • Environmental Health
  • Pediatric Toxicology
  • Consumer Product Safety

Background:

  • Oral products are commonly used by children under three.
  • Phthalates are plasticizers found in many consumer products and are potential endocrine disruptors.
  • Assessing infant exposure to phthalates is crucial for public health.

Purpose of the Study:

  • To determine the prevalence of oral product use in children under three years of age.
  • To quantify phthalate concentrations in these products.
  • To estimate the daily phthalate intake in young children.

Main Methods:

  • Household interviews with 199 mothers in Toluca, Mexico.
  • Analysis of oral product samples using gas chromatography.
  • Calculation of daily phthalate intake based on product concentrations and usage.

Main Results:

  • Oral product use prevalence was 13% among children under three.
  • Higher usage was observed in male infants from lower socioeconomic backgrounds.
  • Mean daily phthalate exposure was 13.94 microg/kg/day, with concentrations up to 67% by weight.

Conclusions:

  • Phthalate intake from oral products did not exceed international limits.
  • Potential for increased total phthalate dose from other sources exists.
  • Further investigation into additional exposure routes and biomarker assessment is recommended due to phthalates' reproductive toxicity concerns.
Abstract

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