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Related Experiment Videos

Personality dimensions in first-episode psychoses.

Matcheri S Keshavan1, Harpreet S Duggal, Gautami Veeragandham

  • 1Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. keshavanms@upmc.edu

The American Journal of Psychiatry
|December 31, 2004
PubMed
Summary

First-episode schizophrenia patients exhibit higher scores in Cluster A and C personality dimensions, particularly avoidant personality, compared to other psychosis patients and healthy individuals. This suggests shared neurodevelopmental factors may underlie these conditions.

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neurodevelopmental Disorders

Background:

  • Premorbid personality dimensions may offer insights into the etiology of schizophrenia.
  • Understanding these dimensions can help differentiate schizophrenia from other psychotic disorders.

Purpose of the Study:

  • To compare premorbid personality dimension patterns in first-episode schizophrenia patients versus those with first-episode nonschizophrenia psychoses and healthy controls.
  • To investigate the specificity of these personality dimensions in schizophrenia.

Main Methods:

  • A semistructured interview, the Personality Disorder Evaluation, was used.
  • 63 first-episode schizophrenia patients, 34 first-episode nonschizophrenia psychosis patients, and 77 healthy controls were assessed.

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Main Results:

  • Schizophrenia patients showed higher Cluster A and C (especially avoidant personality) scores.
  • Patients with nonschizophrenia psychoses had higher Cluster B scores.
  • Cluster C scores, particularly avoidant personality, strongly correlated with Cluster A scores.

Conclusions:

  • The link between avoidant personality and schizophrenia aligns with research on nonspectrum personality disorder comorbidity.
  • Shared neurodevelopmental impairments in social cognition may explain the association between schizophrenia and certain Cluster C personality traits.