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Related Experiment Videos

A home infliximab infusion program.

Adria A Condino1, Sara Fidanza, Edward J Hoffenberg

  • 1The Childrens Hospital, University of Colorado Health Sciences Center, Denver, Colorado, USA.

Journal of Pediatric Gastroenterology and Nutrition
|December 31, 2004
PubMed
Summary

Home infliximab infusions for pediatric Crohn disease are safe, cost-effective, and preferred by patients. This approach reduces school absenteeism and healthcare expenses for infliximab therapy.

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Area of Science:

  • Pediatric Gastroenterology
  • Immunology
  • Health Services Research

Background:

  • Infliximab is a key therapy for pediatric inflammatory bowel disease, particularly Crohn disease.
  • However, its administration is often costly and time-intensive.

Purpose of the Study:

  • To evaluate the feasibility and outcomes of a home-based infliximab infusion program for children.
  • Key metrics included cost-effectiveness, safety, and patient satisfaction.

Main Methods:

  • A retrospective chart review of children receiving home infliximab infusions (September 2001-October 2003).
  • Inclusion criteria: compliance, no prior adverse events, remission, and access to pediatric homecare nursing.
  • Data collected on cost, safety incidents, and patient satisfaction.

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Main Results:

  • Ten children received 59 home infusions (7.5-10 mg/kg/dose).
  • Average savings of $1335 per 100 mg infliximab.
  • High patient satisfaction (average 9/10), reduced school absenteeism.
  • Minor IV access issues occurred; no severe adverse events reported.

Conclusions:

  • Home-based infliximab infusions are a safe and cost-effective option for carefully selected pediatric patients.
  • Patient and family preference for home infusions is high due to reduced time away from school and work.