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Related Experiment Videos

Early enteral nutrition does not decrease hypermetabolism associated with burn injury.

Michael D Peck1, Mary Kessler, Bruce A Cairns

  • 1Department of Surgery, University of North Carolina Healthcare, Chapel Hill, North Carolina, USA. mpeck@unc.med.edu

The Journal of Trauma
|December 31, 2004
PubMed
Summary

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Early enteral feeding for burn patients does not decrease energy expenditure. This study found no significant metabolic benefit from initiating nutrition within 24 hours versus 7 days post-burn.

Area of Science:

  • Metabolic response to injury
  • Nutritional support in critical care

Background:

  • Postburn hypermetabolism significantly impacts patient outcomes.
  • Enteral nutrition is crucial for managing metabolic stress in burn patients.
  • The optimal timing for initiating enteral feeding remains debated.

Purpose of the Study:

  • To compare the effects of early versus late enteral feeding on postburn metabolism.
  • To investigate the impact of feeding timing on energy expenditure in burn survivors.

Main Methods:

  • Prospective, randomized study design.
  • Two groups: early enteral feeding (within 24 hours) vs. late enteral feeding (7 days post-injury).
  • Measured Basal Energy Expenditure (BEE) using Harris-Benedict equations and Resting Energy Expenditure (REE) via indirect calorimetry.

Related Experiment Videos

  • Calculated Average Daily Energy Expenditure (DEE) as REE/BEE.

    • Main Results:

    • Groups were comparable in age, burn size, infection rates, and length of stay.
    • Mortality rates were similar (28% early vs. 38% late) and unaffected by inhalation injury.
    • Controlled analysis revealed a trend towards increased DEE in the early feeding group (mean difference 0.17 kcal, p=0.07).

    Conclusions:

    • Early enteral feeding (within 24 hours) does not reduce the average energy expenditure in burn patients.
    • The timing of enteral nutrition initiation does not appear to significantly alter metabolic demands post-burn.
    • Further research may be needed to explore potential benefits or specific patient subgroups.