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Updated: Aug 20, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Therapeutic approach to the epidemic of atrial fibrillation]
1Mount Sinai Medical Center, New York, NY 10029-6574, United States.
Insights
Atrial fibrillation (AF), a common heart rhythm disorder, affects older populations and increases risks of stroke and death. New guidelines offer improved management strategies for this prevalent condition.
Area of Science:
- Cardiology
- Electrophysiology
Context:
- Atrial fibrillation (AF) is the most common cardiac arrhythmia, with prevalence escalating with age, leading to epidemic proportions.
- The condition carries significant risks of thromboembolism and mortality, particularly in elderly patients with underlying cardiac conditions.
Purpose:
- To summarize the clinical presentation and management of atrial fibrillation.
- To highlight the establishment of new clinical guidelines for atrial fibrillation management by major cardiology societies.
Summary:
- Atrial fibrillation presents in three forms: paroxysmal, persistent, and permanent.
- Its heterogeneous nature, occurring with or without heart disease or symptoms, complicates treatment decisions.
- Guidelines developed by the American College of Cardiology, American Heart Association, and European Society of Cardiology provide a consensus-based approach.
Impact:
- The recently published guidelines aim to standardize and enhance the clinical management of patients diagnosed with atrial fibrillation.
- Improved management can potentially reduce the risks of thromboembolism and mortality associated with atrial fibrillation.
Abstract:
Atrial fibrillation is the most frequent arrhythmia found in clinical practice and its prevalence increases with age which explains why it has reached epidemic proportions. The associated risk of thromboembolism and mortality worsen the prognosis in older patients with cardiac abnormalities. There are three kinds of atrial fibrillation according to the clinical relevance of the presentation: paroxysmal, persistent and permanent. Due to the clinically heterogeneous nature of this arrhythmia (it occurs with or without associated heart disease or symptom) and the difficulty of establishing appropriate treatment for each particular case, the American College of Cardiology, the American Heart Association and European Society of Cardiology, have established guidelines for the management of patients with atrial fibrillation. These guidelines were obtained through consensus by a Committee of Experts, after an exhaustive review of the most relevant English literature on atrial fibrillation in human beings from 1980 to 2000. The recent publication of these guidelines should facilitate and notably improve the management of patients with atrial fibrillation.
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