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Updated: Aug 20, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
Endometrial adenocarcinoma associated with subtle lymph-vascular space invasion and lymph node metastasis: a
Jesse K McKenney1, Christina S Kong, Teri A Longacre
1Department of Pathology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA.
Abstract:
Lymph-vascular space invasion has been established as an independent prognostic factor in endometrial adenocarcinoma. Despite the importance of its recognition, the histologic patterns of lymph-vascular space involvement have not been well addressed in the surgical pathology literature. We report three cases of endometrioid adenocarcinoma of the uterine corpus associated with a subtle pattern of lymph-vascular space invasion closely mimicking intravascular histiocytes. Two cases had regional lymph node metastases composed of morphologically similar cells.
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