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Published on: September 20, 2024
First cases of Acanthamoeba keratitis in Slovakia
Frantisek Ondriska1, Martin Mrva, Martin Lichvár
1HPL (Ltd) Microbiological Laboratory, Istrijska 20, 841 07 Bratislava, Slovak Republic. ondriska@hpl.sk
Abstract:
We present the case report of the first identification of Acanthamoeba as a causative agent of keratitis in the Slovak Republic. For the first time, Acanthamoeba sp. Group III was isolated from a 53-year-old patient with keratitis, which was manifested after an injury of the right eye. A delayed visit to a physician as well as a late diagnosis of the illness led to the advanced stage of eye disease. As the treatment with itraconazol and cornea transplantation showed no result, enucleation of the eye was decided. Acanthamoeba ludgunensis was also the causative agent of keratitis in a 39-year-old patient wearing contact lenses. His complaints occurred a month after bathing in a thermal swimming pool. The symptoms presented in the left eye were those of herpetic keratitis, and led to a cloudy cornea with circular infliltrate and poor vision. A prompt clinical and laboratory diagnosis, along with treatment with propamidine-isetionate resulted in a significant improvement of the eye condition. Contact lenses were probably related to another case of Acanthamoeba keratitis. The patient, a 15-year-old girl, kept wearing contact lenses during bathing in various swimming pools and in the sea; her contact lenses were also regularly washed under tap water. Due to the fact that cysts of Acanthamoeba sp. group II were found in the contact lens solution, this is presumed to be the source of the eye infection.
Insights
Acanthamoeba keratitis, an eye infection, was identified for the first time in the Slovak Republic. Cases involved contact lens wear and eye injury, highlighting the need for prompt diagnosis and treatment.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Acanthamoeba keratitis is a severe eye infection, often associated with contact lens wear or ocular trauma.
- Early diagnosis and treatment are crucial to prevent vision loss and preserve the eye.
Observation:
- First identification of Acanthamoeba sp. Group III in a patient with keratitis following right eye injury.
- Acanthamoeba ludgunensis identified as the cause of keratitis in a contact lens wearer after swimming pool exposure.
- Acanthamoeba sp. group II cysts found in contact lens solution, implicating lens use in a 15-year-old girl's keratitis.
Findings:
- Delayed diagnosis and treatment led to enucleation in the first case.
- Prompt diagnosis and propamidine-isetionate treatment resulted in significant improvement in the second case.
- Contact lens contamination with Acanthamoeba cysts is a likely source of infection in the third case.
Implications:
- Highlights the emergence of Acanthamoeba keratitis in the Slovak Republic.
- Emphasizes the importance of proper contact lens hygiene and avoiding water exposure while wearing lenses.
- Underscores the need for increased awareness and timely medical intervention for Acanthamoeba keratitis.
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