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Complex fMRI analysis with unrestricted phase is equivalent to a magnitude-only model
1Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA. dbrowe@mcw.edu
Neuroimage
|January 4, 2005
Abstract:
Due to phase imperfections, voxel time course measurements are complex valued. However, most fMRI studies measure activation using magnitude-only time courses. We show that magnitude-only analyses are equivalent to a complex fMRI activation model in which the phase is unrestricted, or allowed to dynamically change over time. This suggests that improvements to the magnitude-only model are possible by modeling the phase in each voxel over time.