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Comparative sequence analysis and radiation hybrid mapping of two epidermal type II keratin genes in the dog: keratin

K M Credille1, R Guyon, C André

  • 1Department of Pathobiology, Texas A&M University, College Station, TX 77843-4467, USA. kcredille@cvm.tamu.edu

Cytogenetic and Genome Research
|January 4, 2005
PubMed

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Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...