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Related Experiment Videos

[Ocular Behçet disease. Retrospective study].

R M Torres1, B Yáñez, J M Herreras

  • 1Unidad de Inmunología Ocular, Instituto Universitario de Oftalmobiología Aplicada, Universidad de Valladolid, Valladolid, Spain.

Archivos De La Sociedad Espanola De Oftalmologia
|January 4, 2005
PubMed
Summary

Behçet disease (BD) can cause irreversible vision loss. However, with immunosuppressive treatment, 85% of patients with ocular BD experience a good visual prognosis.

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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Context:

  • Behçet disease (BD) is a multisystem inflammatory disorder.
  • Ocular involvement is a common and potentially sight-threatening manifestation of BD.

Purpose:

  • To investigate the clinical characteristics of ocular Behçet disease.
  • To evaluate visual outcomes and treatment responses to immunosuppressive therapies.

Summary:

  • Retrospective review of 17 patients (33 eyes) with ocular BD.
  • Common symptoms include oral ulcers (100%) and skin lesions (88%).
  • Uveitis (anterior, posterior, panuveitis) was prevalent, affecting 59% to 88.1% of eyes. Visual acuity improved in 33.3%, remained stable in 54.5%, and worsened in 12.1%. Colchicine and cyclosporine were primary treatments, with 59% of patients receiving them.

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Impact:

  • Ocular BD can lead to permanent vision impairment.
  • Early and effective immunosuppressive treatment significantly improves visual prognosis in 85% of cases.