Related Experiment Video
Updated: Aug 11, 2026
Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
[Photodynamic therapy for treatment of choroidal neovascularization]
S Pérez Oliván1, C Torrón Fernández-Blanco, E Ferrer Novella
1Servicio de Oftalmología, Hospital Universitario Miguel Servet, Zaragoza, Spain. sperezo@able.es
Purpose:
To evaluate the efficacy of photodynamic therapy with photodynamic therapy (PDT) in the management of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) and myopia.
Methods:
102 eyes with subfoveal or yuxtafoveal CNV underwent visual acuity (VA) testing, ophthalmic examination, and fluorescein angiography. Retreatment of persistent CNV was done after three months.
Results:
CNV was caused by AMD in 75.5% of patients, pathologic myopia in 24.5%. Follow up ranged from 9 to 33 months (mean: 15.94 months). 88% of CNV caused by pathologic myopia was classic and 40% was in lesions caused by AMD. CNV survival was shorter in lesions caused by pathologic myopia with a significant difference (p=0.0018). VA improved in 48% of lesions caused by pathologic myopia and in 28.6% of lesions caused by AMD. We did not observe any severe complication caused by PDT.
Conclusion:
PDT is a moderately effective treatment without complications in treating subfoveal CNV.
