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Updated: Aug 4, 2026
Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Choroidal metastasis from renal cell carcinoma]
J Castro Navarro1, A Señaris González, C M González Rodríguez
1Hospital Universitario Central de Asturias, Universidad de Oviedo, Oviedo, Spain. jcastro@correo.uniovi.es
Choroidal metastasis from renal cell carcinoma is rare, presenting years after primary tumor treatment. This case highlights the challenge in diagnosing this uncommon eye metastasis.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Renal cell carcinoma (RCC) is a primary kidney malignancy.
- Metastasis of RCC to the choroid is an infrequent occurrence.
Observation:
- A 52-year-old male presented with progressive vision loss in his right eye.
- Fundus examination revealed a choroidal mass, indicative of metastasis.
- The patient had a history of right nephrectomy for RCC and right pneumonectomy for lung metastasis.
Findings:
- Enucleation of the affected eye was performed.
- Initial post-operative period showed no progression.
- Recurrence of the choroidal mass was noted within six months.
Implications:
- Choroidal metastasis from RCC can manifest years after initial treatment.
- Variable presentation and non-specific morphology of choroidal masses pose diagnostic challenges.
- Early detection and management are crucial for ocular metastasis of renal cell carcinoma.
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