Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Synthesis of (-)-DAPD.

Marcos L Sznaidman1, Jinfa Du, Amir Pesyan

  • 1Division of Organic Chemistry, Triangle Pharmaceuticals Inc., Durham, North Carolina, USA. msznaidman@norakbio.com

Nucleosides, Nucleotides & Nucleic Acids
|January 5, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum to: Azvudine remodels the local immunosuppressive microenvironment and exhibits sustained anti-tumor effects in combination with anti-PD-1 therapies.

MedScience·2026
Same author

Time-delayed activator-repressor regulation of ginsenoside biosynthesis in Gynostemma pentaphyllum.

The New phytologist·2026
Same author

Discovery of the roles of SmMAPK4 in regulating tanshinone biosynthesis in Salvia miltiorrhiza.

The New phytologist·2025
Same author

Azvudine remodels the local immunosuppressive microenvironment and exhibits sustained anti-tumor effects in combination with anti-PD-1 therapies.

Frontiers of medicine·2025
Same author

Discovery and engineering of the asiaticoside, madecassoside and asiaticoside B biosynthetic pathway.

Plant physiology and biochemistry : PPB·2025
Same author

Identification of a central regulator of ginkgolide biosynthesis in <i>Ginkgo biloba</i> that integrates jasmonate and light signaling.

Proceedings of the National Academy of Sciences of the United States of America·2025

A novel synthesis for (-)-DAPD has been developed, offering a scalable method for large-scale production. This advancement is crucial for the wider availability of this important compound.

Area of Science:

  • Organic Chemistry
  • Synthetic Chemistry

Background:

  • (-)-DAPD is a compound with significant applications.
  • Existing synthesis methods may not be suitable for industrial scale.

Purpose of the Study:

  • To describe a new synthesis of (-)-DAPD.
  • To ensure the developed synthesis is amenable to large-scale production.

Main Methods:

  • A novel synthetic route was designed and executed.
  • Optimization studies were performed to ensure scalability.

Main Results:

  • A new, efficient synthesis of (-)-DAPD was successfully developed.
  • The synthesis is demonstrated to be suitable for large-scale manufacturing.

Related Experiment Videos

Conclusions:

  • The described synthesis provides a viable pathway for industrial production of (-)-DAPD.
  • This work facilitates broader access to (-)-DAPD.