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Related Concept Videos

The Spinal Cord01:54

The Spinal Cord

32.9K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
32.9K
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
7.5K
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

6.4K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
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Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

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Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
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Spinal Cord01:26

Spinal Cord

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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Updated: Apr 13, 2026

Intraoperative Ultrasound in Spinal Surgery
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Intraoperative Ultrasound in Spinal Surgery

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Malignant spinal-cord compression.

Dheerendra Prasad1, David Schiff

  • 1Department of Radiation Oncology, University of Virginia, Charlottesville, VA, USA.

The Lancet. Oncology
|January 5, 2005
PubMed
Summary
This summary is machine-generated.

Malignant spinal-cord compression (MSCC) often delays diagnosis until patients lose mobility. Early detection and aggressive treatment, including surgery and radiation, improve outcomes for cancer patients with MSCC.

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Area of Science:

  • Oncology
  • Neurology
  • Radiotherapy

Background:

  • Malignant spinal-cord compression (MSCC) is a frequent cancer complication impacting patient survival and quality of life.
  • Delayed diagnosis of MSCC is common, often occurring after patients experience ambulation loss.

Purpose of the Study:

  • To review the epidemiology, pathophysiology, and clinical features of MSCC.
  • To discuss optimal management strategies informed by clinical trials, including corticosteroids, radiotherapy, and surgery.

Main Methods:

  • Literature review of epidemiology, pathophysiology, and clinical presentation of MSCC.
  • Analysis of clinical trial data on MSCC management.
  • Emphasis on advances in radiation delivery and surgical debulking.

Main Results:

  • MSCC significantly affects quality of life and survival in cancer patients.
  • Despite diagnostic tools, diagnosis is frequently delayed until motor deficits are present.
  • Randomized trials support aggressive surgical debulking for MSCC.

Conclusions:

  • Optimal management of MSCC involves a multidisciplinary approach.
  • Advances in radiotherapy and surgical techniques enhance treatment efficacy.
  • Timely diagnosis and intervention are crucial for improving outcomes in MSCC.