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Human genetic research: emerging trends in ethics.
Bartha Maria Knoppers1, Ruth Chadwick
1Centre de recherche en droit public, University of Montreal, C.P. 6128, succ. Centre-ville, Quebec H3C 3J7, Canada. knoppers@droit.umontreal.ca
Nature Reviews. Genetics
|January 5, 2005
Summary
Human genetic research has advanced to genome-wide variation studies. This progress is paralleled by a growing focus on ethical principles like reciprocity and universality in genetic science.
Area of Science:
- Genetics
- Bioethics
Background:
- Genetic research has evolved significantly, moving from Mendelian genetics to genome-wide sequence maps.
- The study of natural human genetic variation is now at the genomic level.
Purpose of the Study:
- To highlight the evolution of genetic research methodologies.
- To underscore the concurrent shift towards ethical considerations in the field of human genetics.
Main Methods:
- Review of historical advancements in genetic research.
- Analysis of the changing ethical landscape in genomic studies.
Main Results:
- Demonstration of the progression from basic genetic principles to complex genomic variation analysis.
- Identification of a decade-long emphasis on ethical principles including reciprocity, mutuality, solidarity, citizenry, and universality.
Conclusions:
- Genetic research has reached a new frontier with the study of whole-genome variation.
- Ethical principles are increasingly integral to the practice and advancement of genetic research.