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[Studies on the flavonoids in herb from Scutellaria barbata]
Wen-shu Wang1, Ya-wei Zhou, Yun-hua Ye
1Key Laboratory of Bioorganic and Molecular Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Objective:
To study flavonoids in Scutellaria barbata and elucidate their structures.
Method:
Compounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra.
Result:
Five flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6).
Conclusion:
Flavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.