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Published on: August 7, 2019
[Epidemiologic features of Mediterranean spotted fever in Portugal]
Rita de Sousa1, Sónia Dória Nóbrega, Fátima Bacellar
1Instituto Nacional de Saúde Dr. Ricardo Jorge, CEVDI Aguas de Moura, Lisboa.
Abstract:
Mediterranean spotted fever (MSF) is a tick-borne rickettsial disease. It is endemic in Portugal and Ricardo Jorge recognized it in 1930. Rhipicephalus sanguineus is the main vector and reservoir of the disease. In Portugal the etiologic agents are two strains of Rickettsia conorii complex: R. conorii Malish and "Israeli tick typhus". MSF is clinically characterized by a vasculitis process with the classical clinical triad of fever, rash, and lesion at the site of tick bite. Although the majority MSF cases are considered benign, last years some districts presented more severe cases than expected. The reported incidence of MSF in Portugal for 1989 to 2000 was 9.8/10(5) inhabitants, the highest incidence compared to other mediterranean countries. Alentejo was the region who presents the highest incidence with 31/10(5) inhabitants. Nevertheless, Bragança was the district which appears with greater number of cases, 62/10(5) inhabitants. The highest annual incidence rate reported was among children, peaking in those 1-4 years of age with 60.2/10(5) inhabitants. Observation of mortality rates have shown that Beja district have the highest mortality rates for MSF in Portugal, but in 1997 in this district, mortality have unexpected values with 7.6 deaths per 100,000 inhabitants have occurred. Although is an obligatory notifiable disease, high number of underreported cases are detected.
Insights
Mediterranean spotted fever (MSF), a tick-borne illness, is endemic in Portugal. This study highlights its high incidence, particularly in children, and regional variations in severe cases and mortality.
Area of Science:
- Epidemiology of tick-borne diseases
- Rickettsial infections
- Public health surveillance
Context:
- Mediterranean spotted fever (MSF) is a significant tick-borne rickettsial disease in Portugal, endemic since 1930.
- Rhipicephalus sanguineus ticks are the primary vectors and reservoirs for Rickettsia conorii strains causing MSF.
- The disease presents with fever, rash, and a tick bite lesion, typically benign but with recent reports of increased severity.
Purpose:
- To analyze the incidence, regional distribution, and demographic patterns of Mediterranean spotted fever in Portugal.
- To investigate trends in MSF severity and mortality, particularly in specific districts and age groups.
- To assess the underreporting of this notifiable disease in Portugal.
Summary:
- Portugal exhibits the highest incidence of MSF in Mediterranean countries (9.8/10^5 inhabitants, 1989-2000), with Alentejo and Bragança showing high regional rates.
- Children aged 1-4 years have the highest incidence (60.2/10^5 inhabitants).
- Beja district recorded the highest MSF mortality, with an unusual spike in 1997 (7.6/100,000).
Impact:
- This research underscores the substantial public health burden of MSF in Portugal, necessitating enhanced surveillance and control strategies.
- Findings emphasize the need to address regional disparities and age-specific risks associated with MSF.
- The study highlights significant underreporting, indicating a need for improved diagnostic and notification practices for this tick-borne illness.
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