Related Experiment Video
Updated: Aug 20, 2026
Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Hearing loss and extent of labyrinthine injury in Pseudomonas otitis media
John Malaty1, James C Lee, Mei Zhang
1Department of Otolaryngology, University of Florida, Gainesville 32610-0264, USA.
Objectives:
To determine if the severity of hearing loss due to semicircular canal transection (SCT) in Pseudomonas otitis media (POM) is a function of the extent of the labyrinthine injury.
Methods:
POM was induced bilaterally in 45 guinea pigs. After 2 to 4 days, SCT was performed in one 1 on the horizontal canal, the superior canal, or both the horizontal and the superior canals. Auditory-evoked brainstem responses were measured before and after SCT.
Results:
POM was induced bilaterally in all animals. Elevation of click thresholds was found in almost all SCT ears of all 3 groups; however, there were no significant differences between groups. Comparing the SCT ear to the contralateral, control ear, mean hearing losses in the horizontal, superior, and horizontal + superior SCT groups were 23 dB, 27 dB, and 24 dB, respectively.
Conclusions:
Hearing loss does not correlate with extent of labyrinthine injury in POM in the guinea pig.
Ebm Rating:
B-2.
