Related Experiment Video
Updated: Aug 20, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
[Clinical importance of CMV-infection in German-speaking burn centers]
M Pfau1, K Hamprecht, H-E Schaller
1Klinik für Hand-, Plastische, Rekonstruktive und Verbrennungschirurgie, Berufsgenossenschaftliche Unfallklinik, Eberhard-Karls-Universität Tübingen, Schnarrenbergstrasse 95, 72076 Tübingen, Germany.
Abstract:
Due to immunosuppression, burn patients are at risk for CMV-infection. By means of a retrospective questionnaire we evaluated the clinical rating and management of CMV-infection in German-speaking burn centers. 41 % of the participating burn centers considered the role of CMV-infection of overall minor importance, 41 % of importance only in intensive care burn patients, 18 % of overall great importance. 70 % of the participating burn centers do not perform CMV-screening at admission. More than 50 % of the participating burn centers consider application of CMV-negative human blood-derived products in CMV-seronegative individuals as essential. At present clinical importance of CMV-infection in burn patients can not be clearly determined. But further prospective studies utilizing recently developed diagnostics seem warranted to the potential influence of CMV-infection on morbidity and mortality in burn patients.
Insights
Burn patients face Cytomegalovirus (CMV) infection risks due to immunosuppression. Current clinical management and screening practices in German burn centers vary, highlighting a need for further research on CMV
Area of Science:
- Infectious Diseases
- Burn Care
- Immunocompromised Patients
Background:
- Burn patients are susceptible to Cytomegalovirus (CMV) infection due to immunosuppression.
- The clinical significance of CMV infection in burn patients remains unclear.
- Current management and diagnostic approaches for CMV in burn care settings require evaluation.
Purpose of the Study:
- To assess the clinical recognition and management strategies for CMV infection in German-speaking burn centers.
- To identify current practices regarding CMV screening and the use of CMV-negative blood products.
- To determine the perceived importance of CMV infection in burn patient care.
Main Methods:
- A retrospective questionnaire-based study was conducted.
- The survey targeted burn centers in German-speaking regions.
- Data collected focused on clinical rating, management, screening, and prevention of CMV infection.
Main Results:
- A significant portion of burn centers (41%) consider CMV infection of minor importance.
- Only 18% of centers view CMV infection as of great overall importance.
- Most centers (70%) do not screen for CMV upon admission, though over 50% deem CMV-negative blood products essential for seronegative patients.
Conclusions:
- Clinical importance of CMV infection in burn patients is not clearly established.
- Current practices in German burn centers show variability in CMV management and screening.
- Prospective studies using advanced diagnostics are needed to clarify CMV's impact on burn patient outcomes.
More Related Videos
08:08qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue
Published on: July 9, 2014
08:04Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
Related Concept Videos
Cytomegalovirus Disease
Cryptococcal Meningitis
Genital Herpes
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Candidiasis