Management of patients with chronic kidney disease presenting with acute coronary syndrome
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Published on: April 4, 2025
Jeremy J Lum1, James R Madison, Todd B Seto
1University of Hawaii John A Burns School of Medicine, Department of Internal Medicine, Honolulu, HI 96813-2427, USA. lumjj@hawaii.rr.com
Insights
Patients with chronic kidney disease (CKD) experience longer hospital stays and delayed treatment for acute coronary syndromes (ACS). They also undergo fewer diagnostic angiographies compared to patients without CKD.
Area of Science:
- Cardiology
- Nephrology
- Clinical Medicine
Background:
- Acute coronary syndromes (ACS) are a leading cause of mortality worldwide.
- Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease.
- Optimal management of ACS in CKD patients remains a challenge.
Purpose of the Study:
- To investigate the treatment patterns of patients with CKD presenting with ACS.
- To compare the management of ACS in patients with and without CKD.
Main Methods:
- Retrospective chart review of 400 patients.
- Inclusion of patients with and without diagnosed CKD.
- Analysis of hospital stay duration, diagnostic angiography rates, and time to therapy.
Main Results:
- Patients with CKD had significantly longer hospital stays.
- CKD patients received fewer diagnostic angiographies.
- A delay in initiating therapy was observed in patients with CKD.
Conclusions:
- CKD is associated with suboptimal ACS treatment patterns.
- Further research is needed to optimize ACS management in CKD patients.
- Addressing these disparities may improve outcomes for CKD patients with ACS.
Abstract:
We evaluated the treatment pattern of patients with chronic kidney disease presenting with acute coronary syndromes. In a retrospective chart review of 400 patients with and without kidney disease presenting with angina pectoris we found that patients with chronic kidney disease have longer hospital stays, receive fewer diagnostic angiographies, and have a delay in therapy.
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