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Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment
Published on: May 6, 2020
[What risk is a health care worker infected with hepatitis B or C virus for his patients?]
Insights
Healthcare workers in the Czech Republic with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection lack legislative standards for high-risk procedures. International guidelines vary, necessitating a consensus for patient safety.
Area of Science:
- Hepatology and Infectious Diseases
- Occupational Health and Safety
- Public Health Policy
Context:
- Absence of specific legislation in the Czech Republic regarding healthcare workers (HCWs) with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection performing high-risk procedures.
- Discrepancies in international regulations concerning HCWs with chronic HBV/HCV, with some nations restricting HBeAg-positive HBV individuals from invasive interventions.
- The critical role of viremia assessment (serum HBV DNA levels) in managing HBV-infected HCWs, particularly those with HBeAg-minus mutants.
Purpose:
- To highlight the current legislative gap in the Czech Republic concerning HCWs infected with HBV or HCV.
- To compare existing international practices and recommendations for managing HCWs with chronic viral hepatitis.
- To underscore the need for establishing clear guidelines and consensus on managing HCWs with HBV/HCV to ensure patient safety.
Summary:
- Currently, no Czech laws prohibit healthcare workers with chronic HBV or HCV from performing procedures that risk transmission.
- While some countries restrict HBV-infected HCWs based on viremia levels, HCV transmission risk is lower, often not leading to restrictions.
- International recommendations from 12 European countries and the USA offer a basis for developing a unified approach.
Impact:
- The findings emphasize the urgent need for the Czech Republic to develop legislative standards and clear policies for HCWs with chronic viral hepatitis.
- Establishing consensus and implementing standardized guidelines will enhance patient safety and protect public health.
- This study serves as a precursor to necessary policy changes, aligning the Czech Republic with international best practices.
Abstract:
Presently, there are no legislative standards in the Czech Republic banning health care workers with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection to do activities with a risk of the transmission of these viral infections to patients (surgeries and other invasive interventions). In a range of developed countries in the world individuals with chronic HBV infection, HBeAg positive individuals, have a restricted access to the risk interventions. A quantitative assessment of viremia is important in the health care workers infected with HBeAg-minus mutant of the virus. There are particular critical viremia values set up (serum HBV DNA levels) which exceeding in the health care workers leads to banning them to do the risk interventions. In cases of proved transmission of hepatitis B infection from a health care worker to a patient, the ban of doing risk interventions is a rule. Transmission of HCV infection from a health care worker to a patient is much less probable so the individuals with chronic hepatitis C are usually not forbidden to make invasive procedures. An exception are cases when there was a patient infected by a particular health care worker in the past. There are various attitudes to the health care workers with chronic HBV or HCV infection in various countries of the world. A necessity to reach a definite consensus is necessary. The first step to it are common recommendations of 12 European countries and the USA which are repeatedly cited in the text. We can expect that these problems will have to be solved very soon in the Czech Republic too.
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