Cheiro-oral-pedal syndrome.

Area of Science:

• Neurology
• Neuroscience
• Medical Case Reports

Background:

• The cheiro-oral syndrome, characterized by sensory disturbances in the mouth and hand, is a recognized neurological condition.
• Previous literature has not documented cases involving concurrent sensory disturbances in the mouth, hand, and foot on the same side.

Observation:

• This report details two novel cases of a cheiro-oral-pedal syndrome.
• Patients presented with a unique pattern of sensory disturbance affecting the ipsilateral mouth, palm, and foot.

Findings:

• Magnetic resonance imaging (MRI) confirmed the neurological lesions responsible for the cheiro-oral-pedal syndrome.
• Lesions were localized to the medial lemniscus and the ventral ascending tract of the trigeminal nerve.

Implications:

• This study introduces and defines the cheiro-oral-pedal syndrome as a distinct clinical entity.
• Understanding these specific lesion locations advances knowledge of somatosensory pathways and their clinical manifestations.