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Published on: January 28, 2020
[Cytokines in cardiovascular diseases. Role in pathogenesis, effect on prognosis, therapeutic perspectives]
Insights
Elevated cytokines are linked to cardiovascular diseases, impacting heart and vascular health. Research explores these cytokine roles in disease development and potential therapeutic strategies.
Area of Science:
- Biochemistry
- Immunology
- Cardiology
Context:
- Over the past decade, numerous studies have documented elevated serum cytokine concentrations in most cardiovascular diseases.
- Cytokines are recognized to influence cardiac muscle and vascular wall function, affecting patient prognosis.
Purpose:
- To review current findings on the significance of cytokines in cardiovascular disease pathogenesis.
- To explore potential therapeutic interventions targeting cytokines in cardiovascular diseases.
Summary:
- Cytokines play a crucial role in the development and progression of cardiovascular diseases.
- Evidence links specific cytokine profiles to adverse outcomes in patients with cardiovascular conditions.
- The cytokine hypothesis of cardiovascular diseases is increasingly supported by scientific literature.
Impact:
- Understanding cytokine involvement offers new avenues for diagnosing and managing cardiovascular diseases.
- Targeting cytokine pathways presents a promising strategy for novel cardiovascular therapies.
- This review provides a comprehensive overview for researchers and clinicians in the cardiovascular field.
Abstract:
During the last ten years many papers were published providing evidence of elevated serum concentrations of different cytokines in the majority of cardiovascular dieseases. Eventually it was demonstrated that they exert various effects on the heart muscle and vascular wall and thus have an impact on the patient's prognosis. Nowadays even a cytokine hypothesis of cardiovascular diseases exists. The objective of the work is to give an account of contemporary findings on the importance of cytokines in the pathogenesis of cardiovascular diseases and possibilities of therapeutic interventions.
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