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[Cytoimunofluorometry and its use in the detection of blood platelet activation]

M Loudová1, J Krejsek, O Kopecký

  • 1Ustav klinické imunologie a alergologie Fakultní nemocnice, Hradec Králové.

Vnitrni Lekarstvi
|January 8, 2005
PubMed

Blood platelet activation is a complex process involved in the physiological hemostasis and also in a number of disorders. Platelets change their morphology, modify their surfaces glycoprotein receptors with adhesive functions. Procoagulant microparticles are shedding and the aggregates of platelets with leucocytes are appearing. The activated platelet can be detected by flow cytometry after imunofluorescent staining.

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