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Updated: Aug 20, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
[Optic nerve damage in multiple sclerosis patients]
Marek Rekas1, Rafał Pawlik, Joanna Wierzbowska
1Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie.
Purpose:
The aim of the work was to catch the type of damage of optic nerve in the group of patients with multiple sclerosis.
Material And Methods:
The examinations were held on 77 eyes of 40 patients with multiple sclerosis. Among them 11 patients had previous optic neuritis, 29 have not problems with vision. The examination was conducted by CSV-1000 contrast test depict on contrast sensitivity function and anomaloscopy AN-69 appointing coefficient eta and threshold of red, green and blue hue.
Results:
As a result, two groups of selective damage and one of non-selective eyes were obtained. In 5 eyes (6.5% examined group eyes) were selective damage of contrast sensitivity in 18 cdg connected with increased threshold for blue hue. The second group of 4 eyes (5.2% examined eyes) were characteristic by damage of contrast sensitivity in 12 cdg and increased threshold of red hue on the border of probable protanomaly. The rest 60 eyes (77.9% the examined group) were non-selective in psychophysical tests. In the eyes of that group were stated non-specific dyschromatopsy connected with equal decrease of contrast sensitivity function, with the tendency to serious changes in high spatial frequency.
Conclusions:
Psychophysical tests enable early diagnosis and monitoring of optic nerve damage in multiple sclerosis patients.
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