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Updated: Aug 3, 2026
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Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development
Published on: March 24, 2011
[A decade of experience in craniofacial surgery]
M R Wexler1, A Neuman, F Umanski
1Dept. of Plastic Surgery, Hadassah-University Hospital, Jerusalem.
Harefuah
|February 2, 1992
Summary
This study highlights the success of pediatric craniofacial surgery in treating complex malformations like Crouzon syndrome and craniostenosis. Early surgical intervention supports normal development and growth in young patients.
Area of Science:
- Craniofacial Surgery
- Pediatric Surgery
- Plastic Surgery
Context:
- Multidisciplinary team approach involving plastic surgery, neurosurgery, ophthalmology, genetics, neurology, orthodontics, pedodontics, facial rehabilitation, psychiatry, social work, and anesthesiology.
- Craniofacial surgery has evolved into a predominantly pediatric subspecialty.
- Evidence supports that early, precise surgical interventions do not impede normal growth and development.
Purpose:
- To review surgical outcomes for various craniofacial malformations.
- To present a series of 78 patients treated between 1979-1989.
- To illustrate the efficacy of surgical repair through case examples.
Summary:
- Surgical repairs addressed Crouzon and Apert syndromes, hypertelorism, large craniofacial clefts, and craniostenosis.
- Procedures included frontal remodelling, mid-facial advancement, orbital repositioning, and cranial vault reconstruction.
- The study encompasses a decade of patient data, detailing complex reconstructive techniques.
Impact:
- Demonstrates the feasibility and positive outcomes of early surgical correction for craniofacial anomalies.
- Highlights the importance of a comprehensive, multidisciplinary team in managing complex pediatric cases.
- Provides valuable insights into surgical techniques for congenital and acquired craniofacial deformities.
