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Myocardial function in severe aortic stenosis before and after aortic valve replacement: a Doppler tissue imaging
Davide Giorgi1, Vitantonio Di Bello, Enrica Talini
1Cardiac and Thoracic Department, University of Pisa, 56124 Pisa, Italy
Summary
Pulsed-wave Doppler tissue imaging (DTI) effectively detects systolic and diastolic dysfunction in severe aortic stenosis patients. DTI parameters correlate with aortic stenosis severity, aiding in understanding myocardial function.
Area of Science:
- Cardiology
- Echocardiography
- Medical Imaging
Background:
- Severe aortic stenosis (AS) significantly impacts cardiac function.
- Assessing diastolic and systolic function in AS is crucial for patient management.
Purpose of the Study:
- To evaluate the utility of Pulsed-wave Doppler tissue imaging (DTI) in assessing cardiac function in severe AS patients.
- To correlate DTI findings with the severity of aortic stenosis.
Main Methods:
- Thirty-five AS patients and 35 healthy controls underwent conventional echocardiography and DTI.
- AS patients were stratified into groups based on heart failure signs and left ventricular systolic function.
- Symptomatic AS patients were reassessed after surgical aortic valve replacement.
Main Results:
- DTI identified significant abnormalities in systolic (S velocity) and diastolic (E velocity, A velocity, E/A ratio) function in AS patients compared to controls.
- These DTI abnormalities were more pronounced in symptomatic AS patients with reduced ejection fraction.
- A significant inverse correlation was observed between DTI parameters and AS peak/mean gradients.
Conclusions:
- DTI is a valuable tool for detecting systolic and diastolic myocardial dysfunction in severe AS.
- DTI parameters provide insights into the physiopathological impact of AS on cardiac function.
- DTI findings correlate with AS severity, aiding in clinical assessment.