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Increased TGF-beta2 in severe asthma with eosinophilia

Silvana Balzar1, Hong Wei Chu, Phillip Silkoff

  • 1Department of Medicine, National Jewish Medical and Research Center and University of Colorado Health Sciences Center, Denver 80206, USA. balzars@njc.org

The Journal of Allergy and Clinical Immunology
|January 8, 2005
PubMed
Summary

Transforming growth factor-beta 2 (TGF-beta2) is elevated in severe asthma, primarily from eosinophils, and linked to profibrotic responses. This suggests a partially activated TGF-beta pathway in all asthma patients.

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