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Updated: Aug 20, 2026

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
Published on: October 18, 2011
Complications of radiation therapy on the brain and spinal cord
Anthony Béhin1, Jean-Yves Delattre
1Fédération de Neurologie Mazarin, Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.
Abstract:
Various nervous system complications can result from radiation therapy. Usually classified according to the timing of onset after irradiation, these complications can be debilitating and even life-threatening. A better knowledge of the risk factors has allowed the definition of "safe" procedures that have reduced the incidence of severe sequelae. This review addresses the main clinical, radiological, biological, and therapeutic issues pertaining to the side effects of radiation therapy on the brain and spinal cord, including radiation-induced vascular and endocrine complications.
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