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Autonomic dysfunction in rheumatic diseases.

Rainer H Straub1, Christoph G Baerwald, Matthias Wahle

  • 1Laboratory of Neuroendocrinoimmunology, Department of Internal Medicine I, University Hospital Regensburg, 93042 Regensburg, Germany. rainer.straub@klinik.uni-regensburg.de

Rheumatic Diseases Clinics of North America
|January 11, 2005
PubMed
Summary

Autonomic nervous system (ANS) dysfunctions are common in rheumatic diseases, potentially contributing to disease development. Further research is needed to better understand these ANS alterations.

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Area of Science:

  • Rheumatology
  • Neurology
  • Autonomic Nervous System Research

Background:

  • Rheumatic diseases frequently involve autonomic nervous system (ANS) dysfunctions.
  • These dysfunctions can stem from peripheral autonomic neuropathy or central nervous system changes.
  • Complex regional pain syndromes (CRPS) represent a specific manifestation of ANS dysfunction.

Purpose of the Study:

  • To describe the prevalence of autonomic dysfunctions in patients with rheumatic diseases.
  • To demonstrate complex regional pain syndromes as a form of ANS dysfunction.
  • To highlight the role of ANS alterations in the pathogenesis of rheumatic diseases.

Main Methods:

  • Review of clinical presentations of autonomic dysfunctions in rheumatic diseases.
  • Description of the clinical characteristics of complex regional pain syndromes.

Related Experiment Videos

  • Discussion of the involvement of the autonomic nervous system in rheumatic conditions.
  • Main Results:

    • Autonomic dysfunctions are prevalent in patients with rheumatic diseases.
    • Complex regional pain syndromes exhibit characteristic symptoms including pain, movement disorders, and altered physiological regulation.
    • Evidence suggests ANS alterations are implicated in the pathogenesis of rheumatic and related diseases.

    Conclusions:

    • Alterations in the autonomic nervous system are observed in rheumatic and related diseases.
    • These ANS changes may play a role in the pathogenesis of these conditions.
    • More sophisticated methods are required for studying ANS alterations in rheumatic diseases.