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STR data for the 13 CODIS loci in Singapore Malays
H C Ang1, R Sornarajah, S E S Lim
1DNA Profiling Laboratory, Centre for Forensic Science, Health Sciences Authority, 11 Outram Road, Singapore 169078, Singapore. ang_hwee_chen@hsa.gov.sg
Forensic Science International
|January 11, 2005
Summary
Allele frequencies for 13 Combined DNA Index System (CODIS) short tandem repeat (STR) loci were determined in 197 Malays in Singapore. These findings provide crucial data for forensic DNA profiling and population genetics in this demographic group.
Area of Science:
- Forensic Science
- Population Genetics
- Molecular Biology
Background:
- The Combined DNA Index System (CODIS) uses 13 short tandem repeat (STR) loci for forensic identification.
- Understanding population-specific allele frequencies is essential for accurate DNA database matching and forensic investigations.
Purpose of the Study:
- To determine the allele frequencies for the 13 CODIS STR loci in the Malay population residing in Singapore.
- To provide foundational data for the application of CODIS STR markers in forensic casework and genetic studies within this population.
Main Methods:
- Genotyping was performed using the AmpFISTR Profiler Plus and AmpFISTR Cofiler kits.
- DNA samples were analyzed from 197 unrelated individuals of Malay ethnicity in Singapore.
Main Results:
- Allele frequency data for each of the 13 CODIS STR loci were generated.
- The distribution of allele frequencies provides a genetic profile for the studied Malay population.
Conclusions:
- The determined allele frequencies are valuable for forensic DNA analysis in Singapore.
- This study contributes to the global understanding of STR locus variation in different ethnic groups.