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Published on: August 15, 2018
Repeat sudden unexpected and unexplained infant deaths: natural or unnatural?
R G Carpenter1, A Waite, R C Coombs
1Medical Statistics Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. bob.carpenter@lshtm.ac.uk
Insights
Repeat unexpected infant deaths are typically natural, not unnatural. This study found a ratio of 6.7 natural to unnatural deaths among infants in the Care of Next Infant programme.
Area of Science:
- Pediatrics
- Forensic Pathology
- Public Health
Background:
- Previous suggestions indicated a higher likelihood of unnatural causes for recurrent unexplained infant deaths.
- The Care of Next Infant (CONI) programme supports families experiencing such tragedies.
Purpose of the Study:
- To estimate the probability of a second infant death being natural versus unnatural.
- To investigate the causes of death in infants within families with a history of sudden infant death syndrome (SIDS).
Main Methods:
- A cohort of 6373 infants enrolled in the CONI programme by December 1999 was studied.
- Detailed investigations included family interviews, autopsy reviews, and case discussions for CONI deaths.
- Data from England, Wales, and Northern Ireland were analyzed.
Main Results:
- 57 (8.9 per 1000) CONI infants died; 48 were unexpected deaths.
- Of 46 first CONI deaths, 40 were natural and six were probable homicides.
- 18 families experienced two sudden infant death syndrome deaths; two had probable double homicides.
Conclusions:
- Repeat unexpected infant deaths are predominantly natural.
- The study provides statistical evidence to counter the assumption of unnatural causes in recurrent infant deaths.
Background:
There have been suggestions that when two or three unexpected unexplained infant deaths occur within a family they are more likely to be unnatural than natural. We aimed to estimate the probability that a second infant death is natural versus unnatural.
Methods:
The Care of Next Infant programme (CONI) supports parents who have previously had an unexpected and apparently unexplained infant death and is currently available in over 90% of health districts in England, Wales, and Northern Ireland. We studied all deaths in 6373 infants who had completed the CONI programme by December, 1999. After a CONI death, we made detailed enquiries into the previous death and the CONI death, including a family interview, a review of autopsies, and case discussion.
Findings:
57 (8.9 per 1000) CONI infants died. Nine deaths were inevitable, and 48 were unexpected. 44 families lost one child, and two families lost two children. Of the 46 first CONI deaths, 40 were natural; the other six were probable homicides, five committed by one or both parents (two criminally convicted). The ratio of 40 natural to six unnatural deaths is 6.7 (95% CI 2.8-19.4). Enquiries identified 18 families with two SIDS(sudden infant death syndrome) deaths and two families with probable covert double homicides (ratio 9.0 [2.2 to 80.0]). There were no convictions in 13 incomplete cases. Families with three deaths are reported.
Interpretation:
Repeat unexpected infant deaths are most probably natural.
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