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Generation of Genetically Modified Mice through the Microinjection of Oocytes
Published on: June 15, 2017
[Research progress and prospect of animal gene targeting]
Xiang-Ping Li1, Wei-Zhuo Xu, Ning Li
1National Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100094, China.
Abstract:
Established upon the embryo stem cell technique and homologous recombination, gene targeting has been widely used in the genome specific manipulation, especially applied in the genetic trait modification of transgenic animal. Our paper reviewed the history of transgenic animal, somatic cloning and gene targeting, which indicates the influence towards the current status and prospect of the transgenic animal production.
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