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[Analysis of subpopulation in Guangdong Han population]
De-Jian Lv1, Qiu-Ling Liu, Hui-Ling Lu
1Department of Forensic Serology, Zhongshan Medical College of Sun Yat-sen University, Guangzhou 510089, China. dejian@gzsums.edu.cn
Abstract:
To investigate the subpopulation structure within the Han Population in Guandong area, a total of 471 DNA samples from five populations in Guandong Province, including Guangzhou, Foshan, Dongguan, Jiangmen and Zhongshan-Zhuhai region, were genotyped at 15 STR(short tandem repeats) markers. Hardy-Weinberg tests were performed, allele frequencies were compared, and the genetic coancestry coefficient(FST) was estimated. The results did not show significant departure from Hardy-Weinberg equilibrium in the total population. Difference of allele frequencies among these populations was not observed, and the coancestry coefficient(FST)was less than 0.01. Subpopulation structure within Han Population in Guandong Province could not be detected.
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