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Updated: Aug 15, 2026
Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
Peripheral ameloblastoma of the gingiva: the importance of diagnosis
Pía López-Jornet1, Ambrosio Bermejo-Fenoll
1University of Murcia, Murcia, Spain. majornet@um.es
Background:
Peripheral ameloblastoma is an extremely rare epithelial odontogenic tumor, limited to the soft tissues of the gums or oral mucosa. Although the lesion is benign, it may be locally aggressive.
Methods:
The present study describes the case of a 31-year-old male presenting a firm, symptomless tumor mass of irregular appearance and measuring approximately 12 mm in diameter, located in the distal zone of 4.7.
Results:
An excision biopsy was performed. The lesion was covered with hyperplastic squamous epithelium, with islets of epithelial cells located at subepithelial level. The cells in the peripheral zone adopted a palisade distribution, and presented the appearance of a lax reticulum at central level. A fibroblastic stroma was observed between the islets. The diagnosis was peripheral ameloblastoma.
Conclusions:
Although the origin of the lesion remains unclear, it is able to recur and undergo malignant transformation. Consequently, peripheral ameloblastoma should not be viewed as a harmless mass.
