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Improving control of hypertension by an integrated approach -- results of the 'Manage it well!' programme
Laszlo A Szirmai1, Csaba Arnold, Csaba Farsang
1National Institute for Sports and Health, Semmelweis University of Medicine, Budapest, Hungary. laszloszirmai@axelero.hu
Insights
The "Manage it well!" programme improved hypertension control significantly. This integrated approach, focusing on patient adherence and regular monitoring, increased blood pressure control rates from 2.9% to 40.9% in a real-world setting.
Area of Science:
- Cardiology
- Public Health
- Clinical Pharmacy
Background:
- Patient non-compliance significantly hinders effective blood pressure control.
- Established measures to improve adherence are not consistently implemented in routine practice.
Purpose of the Study:
- To implement evidence-based adherence measures within an integrated 'Manage it well!' (MIW) program.
- To evaluate the impact of this program on achieving blood pressure control.
Main Methods:
- A prospective, open-cohort study involving 6941 hypertensive patients across 348 primary and 156 secondary care centers.
- An intervention package including patient/physician education, frequent visits, and home blood pressure monitoring was introduced.
- Treatment involved dose titration of trandolapril or verapamil SR, with potential add-on therapies.
Main Results:
- Data from 5468 patients showed baseline hypertension control in only 2.9% of treated individuals.
- Following the MIW program, control rates increased to 40.9% (P < 0.001).
- Significant reductions in office blood pressure were observed (168/97 mmHg to 139/83 mmHg), with no regimen differences.
Conclusions:
- The integrated, patient-centered MIW program demonstrated significant success in improving hypertension treatment outcomes.
- The findings highlight the effectiveness of this approach in a real-world clinical setting.
Background:
Patient non-compliance is a significant contributor to poor blood pressure control. Although measures to improve compliance are known, they are not in routine use.
Objective:
To apply measures based on current recommendations in an integrated approach in the 'Manage it well!' (MIW) programme, and to determine the improvement in blood pressure control.
Design And Setting:
During the prospective open cohort study, 348 primary and 156 secondary care centres enrolled 6941 hypertensive patients and followed them for 6 months.
Interventions:
An integrated intervention package also applicable to everyday practice was introduced to improve treatment adherence, including education programmes for patients and physicians, tight follow-up with frequent office visits and regular home blood pressure measurements. Treatment was based on either trandolapril or verapamil SR with dose titration, with added-on therapy if necessary.
Main Outcome Measure:
Rates of control of blood pressure to < 140/90 mmHg.
Results:
Data were evaluated from 5468 patients, 72% known to have hypertension and 26% newly diagnosed [2% not available (n.a.)]. At baseline only 2.9% of treated patients had their hypertension well controlled (< 140/90 mmHg), but during the programme this increased to 40.9% (P < 0.001). The absolute reduction in office blood pressure was also significant (from 168 +/- 19/97 +/- 11 mmHg to 139 +/- 13/83 +/- 7 mmHg; P < 0.001). No differences in blood pressure control were found between trandolapril and verapamil SR regimens. Office blood pressure was greater than home blood pressure at baseline (168 +/- 19/97 +/- 11 mmHg compared with 151 +/- 17/89 +/- 10 mmHg; P < 0.001), but this difference disappeared at 6 months (139 +/- 13/83 +/- 7 mmHg compared with 140 +/- 13/84 +/- 7 mmHg, respectively).
Conclusions:
The integrated, patient-focused approach used in the MIW programme significantly increases the success of treatment in a 'real-world' setting.
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