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Visual and Microscopic Evaluation of Streptomyces Developmental Mutants
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Visual and Microscopic Evaluation of Streptomyces Developmental Mutants

Published on: September 12, 2018

Characterization of Streptomyces scabies mutants deficient in melanin biosynthesis

Julie Beauséjour1, Carole Beaulieu

  • 1Centre d'Etude et de Valorisation de la Diversité Microbienne, Département de biologie, Université de Sherbrooke, QC, Canada.

Canadian Journal of Microbiology
|January 13, 2005
PubMed

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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